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  1. Trastuzumab emtansine (T-DM1), an antibody–drug conjugate (ADC) of trastuzumab and cytotoxic agent emtansine (DM1), has been approved for the therapy of metastatic HER2-positive breast cancer after prior treat...

    Authors: Peipei Liu, Jiajun Fan, Ziyu Wang, Wenjing Zai, Ping Song, Yongping Li and Dianwen Ju

    Citation: AMB Express 2020 10:107

    Content type: Original article

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  2. Deltamethrin and its major metabolite 3‐phenoxybenzoic acid (3‐PBA) have caused serious threat to the environment as well as human health, yet little is known about their degradation pathways by bacterial co-c...

    Authors: Jie Tang, Qiong Hu, Dan Lei, Min Wu, Chaoyi Zeng and Qing Zhang

    Citation: AMB Express 2020 10:106

    Content type: Original article

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  3. Ophiocordyceps sinensis has been used as a traditional medicine or healthy food in China for thousands of years. Hirsutella sinensis was reported as the only correct anamorph of O. sinensis. It is reported that t...

    Authors: Li-Qun Jin, Zhe-Wen Xu, Bo Zhang, Ming Yi, Chun-Yue Weng, Shan Lin, Hui Wu, Xiang-Tian Qin, Feng Xu, Yi Teng, Shui-Jin Yuan, Zhi-Qiang Liu and Yu-Guo Zheng

    Citation: AMB Express 2020 10:105

    Content type: Original article

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  4. Maslinic acid is an active member of pentacyclic triterpenes predominantly found in dietary plants including hawthorn berries and olive fruit skins. It has been reported to show immense pharmacological and bio...

    Authors: Yusheng Liu, Hongting Lu, Qian Dong, Xiwei Hao and Lingyan Qiao

    Citation: AMB Express 2020 10:104

    Content type: Original article

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  5. Streptococcus suis, a major emerging pathogen in swine and humans, expresses immunoglobulin G (IgG)-binding proteins (IBPs), which contribute to the ability of organism to evasion of host immune system. The objec...

    Authors: Quan Li, Yang Fu, Genglin Guo, Zhuohao Wang and Wei Zhang

    Citation: AMB Express 2020 10:103

    Content type: Original article

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  6. Biogas plants are a widespread renewable energy technology. However, the use of digestate for agronomic purposes has often been a matter of concern. It is controversial whether biogas plants might harbor some ...

    Authors: Alessandra Fontana, Mariangela Soldano, Paolo Bellassi, Claudio Fabbri, Francesco Gallucci, Lorenzo Morelli and Fabrizio Cappa

    Citation: AMB Express 2020 10:102

    Content type: Original article

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  7. Both steatosis and inflammation are key pathological events in the progression of non-alcoholic fatty liver disease (NAFLD). Probiotics are beneficial for the prevention and treatment of NAFLD. Bifidobacterium an...

    Authors: Yan Yan, Chunyan Liu, Shimin Zhao, Xinxu Wang, Jinling Wang, Heping Zhang, Yuzhen Wang and Guofen Zhao

    Citation: AMB Express 2020 10:101

    Content type: Original article

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  8. During cheese ripening, the bacterial strain Pediococcus acidilactici FAM18098 produces the non-proteinogenic amino acid, α-aminobutyrate (AABA). The metabolic processes that lead to the biosynthesis of this comp...

    Authors: Alexander Wenger, Remo S. Schmidt, Reto Portmann, Alexandra Roetschi, Elisabeth Eugster, Laure Weisskopf and Stefan Irmler

    Citation: AMB Express 2020 10:100

    Content type: Original article

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  9. The purpose of this study was to investigate the prevalence, antibiotic resistance and certain virulence genes of the most predominant bacterial pathogens causing BRD. A total of 225 calves; 55 apparently heal...

    Authors: Abdelazeem M. Algammal, Mahmoud E. El-Sayed, Fatma M. Youssef, Shefaa A. Saad, Mahmoud M. Elhaig, Gaber E. Batiha, Wael N. Hozzein and Madeha O. I. Ghobashy

    Citation: AMB Express 2020 10:99

    Content type: Original article

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  10. H9N2 avian influenza virus has spread worldwide, and vaccination with an inactivated virus is currently the major prevention method in China. To further understand the effect of the selection pressure from ant...

    Authors: Hailong Su, Yu Zhao, Lirong Zheng, Shifeng Wang, Huoying Shi and Xiufan Liu

    Citation: AMB Express 2020 10:98

    Content type: Original article

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  11. The clustering of biosynthetic enzymes is used in nature to channel reaction products and increase the yield of compounds produced by multiple reaction steps. The coupling of multiple enzymes has been shown to...

    Authors: Tina Fink, Bojana Stevović, René Verwaal, Johannes A. Roubos, Rok Gaber, Mojca Benčina, Roman Jerala and Helena Gradišar

    Citation: AMB Express 2020 10:97

    Content type: Original article

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  12. Despite the threat of Fusarium dieback posed due to ambrosia fungi cultured by ambrosia beetles such as Euwallacea spp., the wood-degradation mechanisms utilized by ambrosia fungi are not fully understood. In thi...

    Authors: Kiyota Sakai, Aya Yamaguchi, Seitaro Tsutsumi, Yuto Kawai, Sho Tsuzuki, Hiromitsu Suzuki, Sadanari Jindou, Yoshihito Suzuki, Hisashi Kajimura, Masashi Kato and Motoyuki Shimizu

    Citation: AMB Express 2020 10:96

    Content type: Original article

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  13. Infectious bursal disease virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds, thus causing important economic losses in the poultry industry. M...

    Authors: Evangelina Gómez, María Florencia Cassani, María Soledad Lucero, Viviana Parreño, Silvina Chimeno Zoth and Analía Berinstein

    Citation: AMB Express 2020 10:95

    Content type: Original article

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  14. Recent cell culture media for mammalian cells can be abundantly formulated with nutrients supporting production, but such media can be limited to use in host cell culture, transfection, cell cloning, and cell ...

    Authors: Yong Jae Kim, Sang Kyul Han, Seongtae Yoon and Chan Wha Kim

    Citation: AMB Express 2020 10:93

    Content type: Original article

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  15. Lactobacillus casei f1, L. paracasei f2 and L. paracasei f3 with lipolytic activity were isolated and identified from vinasses according to the morphological–physiological properties detection and 16S rDNA analys...

    Authors: Chengran Guan, Zhiqiang Tao, Li Wang, Ruifeng Zhao, Xuan Chen, Xinyuan Huang, Jianbo Su, Zhen Lu, Xia Chen and Ruixia Gu

    Citation: AMB Express 2020 10:91

    Content type: Original article

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  16. Lectins are carbohydrate-binding proteins that play vital roles in many biological processes. In this study, lectins from three Egyptian cultivars (fava bean, lentil, and pea) were isolated by precipitation wi...

    Authors: Magda M. El-Araby, Einas H. El-Shatoury, Mervat M. Soliman and Hanan F. Shaaban

    Citation: AMB Express 2020 10:90

    Content type: Original article

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  17. Affected by the inner properties and the external environmental conditions, medicinal and edible lotus seeds are susceptible to mildew with fungal infection under suitable temperature and humidity conditions, ...

    Authors: Xiaofang Liao, Chaonan Sun, Fang Wei, Lidong Zhou and Weijun Kong

    Citation: AMB Express 2020 10:89

    Content type: Original article

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  18. Biotransformation has the advantages of low cost and environmental protection and is a preferred method for production of compounds. At present, most 2,5-dihydroxymethylfuran (DHMF) is synthesized by chemical ...

    Authors: Ya-nan Hou, Ya-rong Wang, Chun-hui Zheng and Kun Feng

    Citation: AMB Express 2020 10:88

    Content type: Original article

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  19. Present investigation determines the protective effect of Cinnamtannin A2 against chronic renal failure (CRF). 5/6 nephrectomized rat model was used to induced CRF by removing the kidneys and rats were treated...

    Authors: Na Li, Mingzhu Xu, Mei Wu and Guanjie Zhao

    Citation: AMB Express 2020 10:87

    Content type: Original article

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  20. Pennisetum sinese Roxb (P. sinese) is an efficient and economic energy crop for its high productivity, and has been well studied in its application in phytoremediation and fodder production. However, little is kn...

    Authors: Yan He, Lu Lu, Chao Peng, Huilin Li, Jing Zhang, Run Li and Caiquan Zhou

    Citation: AMB Express 2020 10:86

    Content type: Original article

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  21. Discovery of nanopillars on the surface of the insect wings had led to the understanding of its bactericidal property. Nanopillar topography is deterrent to only those bacteria that are attached, or in close c...

    Authors: Banu Pradheepa Kamarajan and Ananthasubramanian Muthusamy

    Citation: AMB Express 2020 10:85

    Content type: Original article

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  22. Raman and Fourier Transform Infrared (FT-IR) spectroscopy was used for investigation of structural differences of bacterial celluloses (BC), obtained by cultivation native and immobilized cells of Gluconacetobact...

    Authors: Nelli Atykyan, Victor Revin and Vitalina Shutova

    Citation: AMB Express 2020 10:84

    Content type: Original article

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  23. We noticed that syphilis patients seem to be more susceptible to diabetes and the lesions often involve the kidneys, but the pathogenesis is not yet completely understood. In this study, microarray analysis wa...

    Authors: Wei Li, Chunyi Luo, Xiaoping Xie, Yongjian Xiao, Feijun Zhao, Jialun Cai, Xiangping Zhou, Tiebing Zeng, Bo Fu, Yimou Wu, Xinhua Xiao and Shuangquan Liu

    Citation: AMB Express 2020 10:83

    Content type: Original article

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  24. Quorum sensing (QS) inhibition by metal-antibiotic complexes is a promising strategy for the management and control of multidrug resistant Pseudomonas aeruginosa infections. We investigated the anti-quorum sensin...

    Authors: Farzaneh Rafiee, Fakhri Haghi, Rahman Bikas, Azam Heidari, Mina Gholami, Anna Kozakiewicz and Habib Zeighami

    Citation: AMB Express 2020 10:82

    Content type: Original article

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  25. Doubts surrounding the potential adverse effects of antimicrobial preservatives have modified the demand of consumers, who increasingly insist on the production of low-level and even preservative-free cosmetic...

    Authors: Chloe Catovic, Sylvia Martin, Stéphane Desaint, Christine Borges, Hélène Lesouhaitier, Florence Roullet, Nadine Bresciani, Anne-Marie Jouault, Valérie Poulet, Joelle Luc, Valérie Joulia, Alain Jupin, Christophe Masson, Alain Crozier and Marc G. J. Feuilloley

    Citation: AMB Express 2020 10:81

    Content type: Original article

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  26. Alzheimer’s disease (AD) and Parkinson’s disease (PD) are neurodegenerative diseases (NDD) characterized by progressive degeneration of the central nervous system, and few medications are available to halt the...

    Authors: Xin Fang, Xiaoting Zhou, Yuqing Miao, Yiwen Han, Jing Wei and Tingtao Chen

    Citation: AMB Express 2020 10:80

    Content type: Original article

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  27. Hops is an almost unique source of the potent phytoestrogen 8-prenylnaringenin (8-PN). As hops contain only low levels of 8-PN, synthesis may be more attractive than extraction. A strain of the Gram-positive Euba...

    Authors: Esther Moens, Selin Bolca, Tom Van de Wiele, Anita Van Landschoot, Jan L. Goeman, Sam Possemiers and Willy Verstraete

    Citation: AMB Express 2020 10:79

    Content type: Original article

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  28. Meyerozyma guilliermondii, a non-conventional yeast that naturally assimilates xylose, is considered as a candidate for biotechnological production of the sugar alternative xylitol. Because the genes of the xylos...

    Authors: Denise Atzmüller, Nadine Ullmann and Alexander Zwirzitz

    Citation: AMB Express 2020 10:78

    Content type: Original article

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  29. The maturation and development of T cells were not completed until T cells were selected in thymus. It was not until the early 1960s that j.f.a.p. discovered the importance of thymus in T cell development. Twe...

    Authors: Seria Masole Shonyela, Bo Feng, Wentao Yang, Guilian Yang and Chunfeng Wang

    Citation: AMB Express 2020 10:76

    Content type: Original article

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  30. Listeria monocytogenes is a Gram-positive bacterium, commonly found in food, water or sewage. This microorganism is capable of forming biofilm on different surfaces such as steel, glass, polypropylene etc. Recent...

    Authors: Katarzyna Grudlewska-Buda, Krzysztof Skowron and Eugenia Gospodarek-Komkowska

    Citation: AMB Express 2020 10:75

    Content type: Original article

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  31. Previously, we identified 49 undeletable chromosomal regions harboring only non-essential genes in the genome of Saccharomyces cerevisiae. We proposed that there might be unknown synthetic lethal combinations of ...

    Authors: Naim Hassan, Farhana Easmin, Yu Sasano, Keisuke Ekino, Hisataka Taguchi and Satoshi Harashima

    Citation: AMB Express 2020 10:73

    Content type: Original article

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  32. Root-knot nematode (RKN) disease is a soil-borne disease. However, most studies on RKN have focused on the screening of agents and the cultivation of resistant varieties, and reports on the interaction of RKNs...

    Authors: Kuo Huang, Qipeng Jiang, Liehua Liu, Shuting Zhang, Chaoli Liu, Haitao Chen, Wei Ding and Yongqiang Zhang

    Citation: AMB Express 2020 10:72

    Content type: Original article

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  33. An exhaustive screening program was applied for scoring a promising l-asparaginase producing-isolate. The recovered isolate was identified biochemically and molecularly and its l-asparaginase productivity was opt...

    Authors: Nada A. Abdelrazek, Walid F. Elkhatib, Marwa M. Raafat and Mohammad M. Aboulwafa

    Citation: AMB Express 2020 10:71

    Content type: Original article

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  34. Ammonia is an essential substance for agriculture and the chemical industry. The intracellular production of ammonia in yeast (Saccharomyces cerevisiae) by metabolic engineering is difficult because yeast strongl...

    Authors: Yukio Watanabe, Kouichi Kuroda, Yuki Tatemichi, Takeharu Nakahara, Wataru Aoki and Mitsuyoshi Ueda

    Citation: AMB Express 2020 10:70

    Content type: Original article

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  35. The present study aims to escalate the production of prophylactic agent zeaxanthin using a screened potential bacterial isolate. For this purpose, a freshwater bacterium capable of producing zeaxanthin was iso...

    Authors: Shristi Ram, Sushma Rani Tirkey, Madhava Anil Kumar and Sandhya Mishra

    Citation: AMB Express 2020 10:69

    Content type: Original article

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  36. In bacterial system, direct conversion of xylose to xylonic acid is mediated through NAD-dependent xylose dehydrogenase (xylB) and xylonolactonase (xylC) genes. Heterologous expression of these genes from Cauloba...

    Authors: M. S. Lekshmi Sundar, Aliyath Susmitha, Devi Rajan, Silvin Hannibal, Keerthi Sasikumar, Volker F. Wendisch and K. Madhavan Nampoothiri

    Citation: AMB Express 2020 10:68

    Content type: Original article

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  37. Directed evolution has been proven as a powerful tool for developing proteins and strains with novel or enhanced features. In this study, a dual selection system was designed to tune the binding specificity of...

    Authors: Xiaoqiang Jia, Yubing Ma, Rongrong Bu, Tingting Zhao and Kang Wu

    Citation: AMB Express 2020 10:67

    Content type: Original article

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  38. The biological synthesis of metal nanoparticles using plant extracts with defined size and morphology is a simple, nontoxic and environmentally friendly method. The present study focused on the synthesis of si...

    Authors: Anush Aghajanyan, Lilit Gabrielyan, Robin Schubert and Armen Trchounian

    Citation: AMB Express 2020 10:66

    Content type: Original article

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  39. The development of novel methods for highly efficient protein purification remains a research focus in the biotechnology field because conventional purification approaches, including affinity purification, gel...

    Authors: Xiao-Feng Zhou, Chen-Lu Zhang, Xue-Ping Gao, Wei-Long Wang, Zheng-Fen He, Feng-Ying Jiang, Yi-Lin Pang, Jiang-Hui Li, Xiao-Jun Ren, Huai-Bin Zhou, Guo-Qiang Tan, Jian-Xin Lyu and Wu Wang

    Citation: AMB Express 2020 10:65

    Content type: Original article

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  40. Methicillin-resistant Staphylococcus aureus (MRSA) strains are distinct from general Staphylococcus strains with respect to the composition of the membrane, ability to form a thicker biofilm, and, importantly, ab...

    Authors: Hun-Suk Song, Tae-Rim Choi, Yeong-Hoon Han, Ye-Lim Park, Jun Young Park, Soo-Yeon Yang, Shashi Kant Bhatia, Ranjit Gurav, Yun-Gon Kim, Jae-Seok Kim, Hwang-Soo Joo and Yung-Hun Yang

    Citation: AMB Express 2020 10:64

    Content type: Original article

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  41. Paraffinic n-alkanes (C22–C30), crucial portions of residual oil, are generally considered to be difficult to be biodegraded owing to their general solidity at ambient temperatures and low water solubility, rende...

    Authors: Jing Chen, Yi-Fan Liu, Lei Zhou, Muhammad Irfan, Zhao-Wei Hou, Wei Li, Serge Maurice Mbadinga, Jin-Feng Liu, Shi-Zhong Yang, Xiao-Lin Wu, Ji-Dong Gu and Bo-Zhong Mu

    Citation: AMB Express 2020 10:63

    Content type: Original article

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  42. Soybean mosaic virus (SMV) is one of the most destructive viral diseases in soybean and causes severe reduction of soybean yield and destroys the seed quality. However, the production of SMV resistant plants b...

    Authors: Hexiang Luan, Wenlin Liao, Yingpei Song, Haopeng Niu, Ting Hu and Haijian Zhi

    Citation: AMB Express 2020 10:62

    Content type: Original article

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  43. Peatlands have acted as C-sinks for millennia, storing large amounts of carbon, of which a significant amount is yearly released as methane (CH4). Sphagnum mosses are a key genus in many peat ecosystems and these...

    Authors: Martine A. R. Kox, Eva van den Elzen, Leon P. M. Lamers, Mike S. M. Jetten and Maartje A. H. J. van Kessel

    Citation: AMB Express 2020 10:61

    Content type: Original article

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  44. In order to achieve high yield of fungal protease in a very cost effective way and to meet its increased market demand, current study deals with the screening of various agro-wastes as carbon source for the pr...

    Authors: Sangeeta Negi, Sapna Jain and Anand Raj

    Citation: AMB Express 2020 10:60

    Content type: Original article

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  45. Anticancer drug like Cisplatin are associated with serious problem like nephrotoxicity. The effect of Kaempferol is a plant-derived flavonoid compound. The present work evaluated the effect of Kaempferol in mo...

    Authors: Zhu Wang, Wansen Sun, Xi Sun, Ye Wang and Meilan Zhou

    Citation: AMB Express 2020 10:58

    Content type: Original article

    Published on:

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