Table 5 Comparison of the loop mediated isothermal amplification (LAMP) with the multiplex polymerase chain reaction (M-PCR) in the detection of the toxigenic Clostridioides difficile
M-PCR for toxigenic Clostridioides difficile | |||
|---|---|---|---|
Positive | Negative | Total | |
LAMP Positive | 13 (26.0%) | 2 (4.0%) | 15 (30.0%) |
LAMP Negative | 0 (0.0%) | 35 (70.0%) | 35 (70.0%) |
Total | 13 (26.0%) | 37 (74.0%) | 50 (100.0%) |
Sensitivity (%) (95% CI) | 100.0% (75.3 to 100.0%) | ||
Specificity (%) (95% CI) | 94.6% (81.8 to 99.3%) | ||
Positive predictive value (%) (95% CI) | 86.7% (62.8 to 96.2%) | ||
Negative predictive value (%) (95% CI) | 100.0% | ||
Test accuracy (%) (95% CI) | 96.0% (86.3 to 99.5%) | ||
Kappa coefficient (κ) | 0.9 | ||