Scheme 1
![Scheme 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13568-020-01064-w/MediaObjects/13568_2020_1064_Sch1_HTML.png)
Cyclophosphamide converted by MroUPO to human drug metabolites. MroUPO transformed of cyclophosphamide (CPA) into the intrinsic active metabolite 4-hydroxy-cyclophsophamide (4-OH-CPA), its tautomer aldophosphamide (APA) and the overoxidized side product 4-ketocyclophsophamide (4-keto-CPA)