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Table 5 Percentages of secondary structure of NZ2114, H1, H2 and H3 in different solutions

From: Design and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus

 

NZ2114

H1

H2

H3

H2O

20 mM

SDS

50% TFE

H2O

20 mM

SDS

50%

TFE

H2O

20 mM

SDS

50% TFE

H2O

20 mM

SDS

50%

TFE

Helix

74.1

24.8

71.7

55.6

51.6

82.9

35.6

26.8

52.6

35.1

35.2

63.8

Antiparallel

2.9

18.9

1.3

3.8

5.3

0.4

7.7

10.3

3.0

9.8

10.5

2.5

Parallel

2.4

9.2

2.9

5.1

5.7

1.4

8.3

9.9

5.5

8.2

8.1

4.0

Beta-turn

13.5

19.0

11.3

14.7

15.8

4.7

16.3

16.5

13.8

17.3

17.7

13.3

Rndm Coil

7.1

28.1

12.8

20.8

21.6

6.6

31.2

36.5

25.1

29.6

28.5

16.4