Co-colonization of methicillin-resistant Staphylococcus aureus and Candida spp. in children with malignancies

AMB Express

Table 5 Correlation between antibiotics usage with the frequency of S. aureus, MRSA, and Candida spp. in nasal samples

Antibiotics	Total (%)	S. aureus	p-value	MRSA	p-value	Candida spp.	p-value
Antibiotic history
Yes	95 (55.9)	10 (10.5)	0.130	3 (3.1)	0.478	4 (4.2)	0.270
No	75 (44.1)	14 (18.7)	0.130	4 (5.3)	0.478	1 (1.3)	0.270
Ciprofloxacin
Yes	19 (11.2)	5 (26.3)	0.105	2 (10.5)	0.136	0 (0)	0.421
No	151 (88.2)	19 (12.6)	0.105	5 (3.3)	0.136	5 (3.3)	0.421
Vancomycin
Yes	19 (11.2)	2 (10.5)	0.633	1 (5.3)	0.790	0 (0)	0.421
No	151 (88.2)	22 (14.6)	0.633	6 (4)	0.790	5 (3.3)	0.421
Cotrimoxazole
Yes	35 (20.6)	0 (0)	0.007	1 ((2.8)	0.674	0 (0)	0.248
No	135 (79.4)	24 (17.8)	0.007	6 (4.4)	0.674	5 (3.7)	0.248
Amikacin
Yes	10 (5.9)	0 (0)	0.186	0 (0)	0.499	0 (0)	0.570
No	160 (94.1)	24 (15)	0.186	7 (4.4)	0.499	5 (3.1)	0.570
Metronidazole
Yes	10 (5.9)	0 (0)	0.186	0 (0)	0.499	0 (0)	0.570
No	160 (94.1)	24 (15)	0.186	7 (4.3)	0.499	5 (3.1)	0.570
Antifungal history
Yes	62 (36.5)	7 (11.3)	0.422	3 (4.8)	0.720	1 (1.6)	0.437
No	108 (63.5)	17 (15.7)	0.422	4 (3.7)	0.720	4 (3.7)	0.437
Voriconazole
Yes	8 (4.7)	1 (12.5)	0.893	0 (0)	0.548	0 (0)	0.614
No	162 (95.3)	23 (14.2)	0.893	7 (4.3)	0.548	5 (3)	0.614
Fluconazole
Yes	13 (7.6)	1 (7.7)	0.489	0 (0)	0.437	0 (0)	0.514
No	157 (92.4)	23 (14.6)	0.489	7 (4.4)	0.437	5 (3.2)	0.514
Nystatin
Yes	28 (16.5)	1 (3.6)	0.080	0 (0)	0.230	0 (0)	0.314
No	142 (83.5)	23 (16.2)	0.080	7 (4.9)	0.230	5 (35.2)	0.314