Co-colonization of methicillin-resistant Staphylococcus aureus and Candida spp. in children with malignancies

AMB Express

Table 4 Correlation between antibiotics usage with the frequency of S. aureus, MRSA, and Candida spp. in oral samples

Antibiotics	Total (%)	S. aureus	p-value	MRSA	p-value	Candida spp.	p-value
Antibiotic history
Yes	95 (55.9)	14 (14.7)	0.794	9 (9.5)	0.509	25 (26.3)	0.065
No	75 (44.1)	10 (13.3)	0.794	5 (6.7)	0.509	11 (4.7)	0.065
Ciprofloxacin
Yes	19 (11.2)	4 (21)	0.357	3 (15.8)	0.204	3 (15.8)	0.542
No	151 (88.2)	20 (13.2)	0.357	11 (7.3)	0.204	33 (21.8)	0.542
Vancomycin
Yes	19 (11.2)	3 (15.8)	0.824	3 (15.8)	0.204	9 (47.4)	0.003
No	151 (88.2)	21 (13.9)	0.824	11 (7.3)	0.204	27 (17.9)	0.003
Cotrimoxazole
Yes	35 (20.6)	1 (2.8)	0.032	1 (2.8)	0.194	3 (8.6)	0.041
No	135 (79.4)	23 (17)	0.032	13 (9.6)	0.194	33 (24.4)	0.041
Amikacin
Yes	10 (5.9)	2 (20)	0.582	1 (10)	0.834	3 (30)	0.481
No	160 (94.1)	22 (13.7)	0.582	13 (8.1)	0.834	33 (20.6)	0.481
Metronidazole
Yes	10 (5.9)	0 (0)	0.186	0 (0)	0.329	1	0.373
No	160 (94.1)	24 (15)	0.186	14 (8.7)	0.329	35 (21.9)	0.373
Antifungal history
Yes	62 (36.5)	8 (12.9)	0.730	5 (8)	0.951	15 (24.2)	0.466
No	108 (63.5)	16 (14.8)	0.730	9 (8.3)	0.951	21 (19.4)	0.466
Voriconazole
Yes	8 (4.7)	2 (25)	0.365	1 (12.5)	0.653	1 (12.5)	0.538
No	162 (95.3)	22 (13.6)	0.365	13 (8)	0.653	35 (21.6)	0.538
Fluconazole
Yes	13 (7.6)	2 (15.4)	0.891	1 (7.7)	0.941	1 (7.7)	0.216
No	157 (92.4)	22 (14)	0.891	13 (8.3)	0.941	35 (22.3)	0.216
Nystatin
Yes	28 (16.5)	2 (7.1)	0.246	2 (7.1)	0.818	6 (21.4)	0.972
No	142 (83.5)	22 (15.5)	0.246	12 (8.4)	0.818	30 (21.1)	0.972