Fig. 9
From: In silico analysis of the Val66Met mutation in BDNF protein: implications for psychological stress
Phylogenetic analysis of BDNF. Phylogenetic analysis of BDNF amino acid conservation shows moderate conservation of the V66M mutation at position 6, indicating its functional or structural relevance. The residue's function in preserving protein stability and intermolecular interactions is supported by the prediction that it will be buried inside the protein structure