Association between erythrocyte membrane fatty acids and gut bacteria in obesity-related cognitive dysfunction

Zhao, Tong; Huang, Hongying; Li, Jinchen; Shen, Jingyi; Zhou, Cui; Xiao, Rong; Ma, Weiwei

doi:10.1186/s13568-023-01655-3

AMB Express

Table 2 Comparison of fatty acid composition of erythrocyte membranes between the two groups

From: Association between erythrocyte membrane fatty acids and gut bacteria in obesity-related cognitive dysfunction

Variable	MCI (n = 49)	Non_MCI (n = 55)	P
C10:0%	0.022 ± 0.154	0.000 ± 0.000	0.294
C11:0%	0.880 ± 4.338	0.041 ± 0.302	0.261
C12:0%	0.264 ± 0.823	0.426 ± 0.792	0.164
C13:0%	0.051 ± 0.305	0.365 ± 1.173	0.212
C14:0%	0.183 ± 0.348	0.498 ± 0.884	0.490
C15:0%	0.982 ± 1.595	0.836 ± 2.251	0.028*
C16:0%	27.995 ± 7.838	30.322 ± 5.245	0.112
C17:0%	0.101 ± 0.160	0.053 ± 0.105	0.101
C18:0%	19.019 ± 6.492	20.331 ± 4.834	0.119
C20:0%	0.000 ± 0.000	0.020 ± 0.086	0.096
C21:0%	0.007 ± 0.052	0.000 ± 0.000	0.294
C23:0%	0.025 ± 0.129	0.000 ± 0.000	0.136
C24:0%	0.000 ± 0.000	0.042 ± 0.144	0.017*
SFA%	49.529 ± 9.672	52.935 ± 9.891	0.082
C14:1%	0.025 ± 0.123	0.031 ± 0.231	0.518
C15:1%	0.028 ± 0.194	0.059 ± 0.311	0.618
C16:1%	0.073 ± 0.149	0.070 ± 0.180	0.574
C17:1%	0.004 ± 0.026	0.010 ± 0.041	0.364
C18:1 n-9%	10.769 ± 2.099	10.292 ± 3.855	0.059
C20:1%	0.041 ± 0.180	0.088 ± 0.224	0.107
C24:1%	0.520 ± 1.048	1.787 ± 2.760	0.011*
MUFA%	11.459 ± 2.398	12.337 ± 4.452	0.398
C18:2 n-6%	13.329 ± 2.889	11.939 ± 3.284	0.014*
C18:3 n-6%	0.014 ± 0.095	0.027 ± 0.156	0.618
C20:3 n-6%	1.170 ± 0.700	0.998 ± 0.647	0.173
C20:4 n-6%	19.413 ± 5.407	16.699 ± 5.148	0.009*
n-6 PUFA%	33.925 ± 7.683	29.663 ± 7.506	0.009*
C18:3 n-3%	0.000 ± 0.000	0.094 ± 0.418	0.030*
C20:3 n-3%	0.437 ± 3.059	0.478 ± 3.513	0.956
C20:5 n-3%	0.000 ± 0.000	0.005 ± 0.035	0.341
C22:6 n-3%	4.614 ± 1.297	4.435 ± 1.505	0.245
n-3 PUFA%	5.051 ± 3.703	5.012 ± 3.971	0.348
C20:2%	0.035 ± 0.108	0.053 ± 0.127	0.375
PUFA%	39.011 ± 8.037	34.728 ± 8.166	0.023*
n-6/n-3%	7.682 ± 1.983	6.812 ± 1.796	0.020*
O3I%	0.046 ± 0.013	0.044 ± 0.015	0.249

The data is represented by mean and SD. MCI: obesity with cognitive impairment group; Non_MCI: obese but cognitively normal group. SFA: Saturated fatty acids; MUFA: Monounsaturated fatty acids; PUFA: Polyunsaturated fatty acids; TFA: Trans fatty acids; n-6: omega-6 fatty acids; n-3: omega-3 fatty acids; O3I: omega-3 index; *P < 0.05

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