Fig. 7
From: Natural compound targeting BDNF V66M variant: insights from in silico docking and molecular analysis
MD simulation modeled structural complex. A–D The deformability is to indicate that residue interact with each other through deformation between protein with different natural compounds therapy against BDNF muted structure. E–H represent Eigenvalue (1) of complexes. Eigenvalues in NMA are not directly linked to the stiffness or hardness of a molecule; instead, they are associated with the energy associated with vibrational modes and deformation. I–L represent RMSF graph of peptide-ligand complex (Vitamin D3, Curcumin, Vitamin C, Quercetin). M–P represent dot map indicate strong residue-residue interaction amonf residue of BDNF (V66M) target peptide