Fig. 2

Overview of transcriptional changes induced by tyrosol in C. auris. Up-regulated (red) and down-regulated (blue) genes were defined as differentially expressed genes (corrected p value of < 0.05), with more than a 1.5-fold increase or decrease in their transcription (tyrosol-treated versus untreated) (A). Summary of gene enrichment analyses and the number of genes affected by C. auris exposure to tyrosol (B–C). The enrichment of up-regulated (B) and down-regulated (C) gene groups was identified using the Candida Genome Database Gene Ontology Term Finder (http://www.candidagenome.org/cgi-bin/GO/goTermFinder) or was tested by Fisher’s exact test. The data sets for the gene groups are available in Supplemental tables S2 and S3 in the supplemental material