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Fig. 6 | AMB Express

Fig. 6

From: Valuable effects of lactobacillus and citicoline on steatohepatitis: role of Nrf2/HO-1 and gut microbiota

Fig. 6

Microscopic pictures of H&E stained liver sections showing normal hepatocytes arranged in radiating plates around central vein (CV) with normal portal areas (PA) and sinusoids in control –ve group. Meanwhile, liver sections from NASH group showing congested blood vessels (red arrow), occluded sinusoids, diffuse hydropic degeneration with macro-vesicular steatosis (arrowheads). Portal fibrosis appears in some sections with foci of hemorrhage (red arrowhead) and few leukocytic cells infiltration (black arrows). Liver sections showing milder pathological changes in the treated groups including: few micro-vesicular steatosis (black arrowheads), mild micro- vesicular (blue arrowheads) intermingled with few macro-vesicular (black arrowheads) steatosis, in C250 group, few macro-vesicular steatosis (black arrowheads) in C500 group, very few micro-vesicular steatosis (blue arrowheads) in C500 + Lacto group. Low magnification X: 100 bar 100, high magnification X: 400 bar 50

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