Fig. 4

Effect of the tested monotherapies and therapeutic combinations on level of: (a) Caspase3, (b) Bax proteins, (c) pentraxin-3 (pg/mL), (d) Fetuin (ng/mL). Data are expressed as means ± SEM. Results are considered significant when P < 0.05. Neg. control: Control group; Neg.+ citi 500: Control + citicoline 500 mg group; Neg.+ Lacto: Control + Lactobacillus; Posit. control: HFD (Fatty liver) group, citi 250 mg: HFD + citicoline 250 mg group; citi 500 mg: HFD + citicoline 500 mg group; citi + Lacto: HFD + citicoline 500 mg + Lactobacillus group. *vs positive group, € vs. negative group, Ě vs. citicoline 250 mg, © vs. citicoline 500