Fig. 2

Effect of the tested monotherapies and therapeutic combinations on serum level of liver enzymes and liver index: (a) AST (U/L), (b) ALT (U/L), (c) ALP (U/L), (d) liver index. Data are expressed as means ± SEM. Results are considered significant when P < 0.05. Neg. control: Control group; Neg.+ citi 500: Control + citicoline 500 mg group; Neg.+ Lacto: Control + Lactobacillus; Posit. control: HFD (Fatty liver) group, citi 250 mg: HFD + citicoline 250 mg group; citi 500 mg: HFD + citicoline 500 mg group; citi + Lacto: HFD + citicoline 500 mg + Lactobacillus group. *vs positive group, € vs. negative group, Ě vs. citicoline 250 mg, © vs. citicoline 500