Identification reproducible microbiota biomarkers for the diagnosis of cirrhosis and hepatocellular carcinoma

AMB Express

Table 2 Clinical characteristics of 82 samples collected in this study

	Disease state (number of samples)				Statistic	P value
	HC (n = 15)	CHB (n = 21)	LC (n = 25)	HCC (n = 21)	Statistic	P value
Gender(M/F)	10/5	14/7	19/6	18/3	2.575	0.462
Age	30.8 ± 6.21	40.14 ± 8.67	48.4 ± 13.16	53.14 ± 10.3	33.69	2.30E-07
BMI	21.55 ± 1.9	21.33 ± 3	22.52 ± 2.95	22.58 ± 3.14	3.29	0.349
PC	232.13 ± 31.28	158.38 ± 52.3	117.6 ± 94.38	121.76 ± 103.17	30.30	1.19E-06
PT	11.49 ± 0.79	13.41 ± 2	14.16 ± 3.82	15.07 ± 3.51	30.52	1.07E-06
TB	12.47 ± 3.39	57.55 ± 60.01	42.24 ± 66.39	22.67 ± 11.64	24.69	1.79E-05
TP	75.26 ± 4.91	69.31 ± 6.65	65.44 ± 7.82	63.5 ± 10.31	21.78	7.24E-05
ALT	19.13 ± 7.03	59.86 ± 29.39	53.6 ± 44.17	45.86 ± 45.26	23.87	2.65E-05
AST	21.67 ± 5.26	62 ± 28.94	70.76 ± 77.31	60.33 ± 57.8	31.17	7.83E-07
AKP	60.2 ± 16.51	96.62 ± 32.87	121 ± 61.13	139.57 ± 148.27	15.09	1.74E-03
AFP	2.19 ± 0.79	71.25 ± 135.66	957.86 ± 4344.36	511.62 ± 888.28	16.39	9.42E-04
TG	4.25 ± 0.58	1.25 ± 0.5	1.11 ± 0.75	0.96 ± 0.69	38.98	1.75E-08
HDL	1.49 ± 0.28	1 ± 0.52	0.87 ± 0.4	1.07 ± 0.42	19.61	2.04E-04
LDL	2.99 ± 0.51	2.18 ± 0.69	2.03 ± 0.82	2.66 ± 1.31	16.24	1.01E-03

Continuous variables were expressed as mean ± standard deviation. Chi-square test was used for gender, and Kruskal–Wallis test was used for other clinical variables
NA indicated not applicable