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AMB Express

Table 1 Minimal inhibitory concentration (MIC) of wild-type roseocin and its variants

From: Phylogeny-guided genome mining of roseocin family lantibiotics to generate improved variants of roseocin

Lantibiotic

MIC against M. luteus ATCC 10240 (µM)

MIC against MSSA ATCC 25923 (µM)

Roseocin (wild-type)

0.5

2

Roseocin L8F

0.5

0.5

Roseocin L8W

0.25

2

Roseocin S12W

0.5

 > 16

Roseocin V22Q

 > 8

 > 16

Nisin

0.0625

2

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