AMB Express

Table 1 MIC (µg/ml) of tavaborole, AN-2718 and Crisaborole against Gram-Positive and Gram-Negative Bacteria

From: Drug synergy discovery of tavaborole and aminoglycosides against Escherichia coli using high throughput screening

Strain	Tavaborole		AN-2718		Crisaborole
S.aureus
Newman ^a	16		64		32
ATCC 43,300 ^a	32		32		4
LZB1 ^a	32		32		32
USA 300 ^a	32		32		8
RJ-2 ^a	64		64		64
SAJ-1 ^a	16		16		16
S.epidermidis
RP62A	16		16		32
E.coli
ATCC 25,922	8		8		> 64
Y9633^b	16		16		> 64
Y0064^b	16		16		> 64
Y9592^b	8		8		> 64
Y9395^b	8		8		> 64
K.pneumoniae
ATCC 700,603	32		32		> 64
WANG^b	32		32		> 64
A.baumannii
ATCC 1195	16		> 64		> 64
P.aeruginosa
PAO1	32		32		> 64

^aRepresents Methicillin-resistant Staphylococcus aureus
^bRepresents multidrug resistant strains

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