Fig. 4
From: Basis for using thioredoxin as an electron donor by Schizosaccharomyces pombe Gpx1 and Tpx1
Multiple sequence alignment of TPxs from S. pombe, S. cerevisiae and humans. The alignment was constructed using the MEGA_X_10.1.8 software. The N-terminal AhpC-TSA domain and C-terminal 1-Cys Prx_C domain which are characteristic of Prxs were identified by searching the SMART database. The catalytic triad (Thr/Ser-Cys-Arg), the resolving residue and the Glu and Arg residues involved in Prx-Trx interaction are indicated by filled cycles, open circles and stars, respectively. Amino acid residues are highlighted according to the biochemical properties of the amino acid residues