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Table 1 The top 20 up- and down-regulated genes in biofilm samples, respectively

From: Transcriptional analysis and target genes discovery of Pseudomonas aeruginosa biofilm developed ex vivo chronic wound model

Gene_id

Gene

Log2FC

(PAO_B/PAO_P)

PAO_B

PAO_P

Gene description

PA0688

lapA

11.32

6237.32

2.60

Alkaline phosphatase L

PA3219

PA3219

9.85

395.65

0.46

Hypothetical protein

PA0842

PA0842

9.60

451.26

0.62

Glycosyl transferase family protein

PA3383

PA3383

9.18

767.95

1.42

Phosphonate ABC transporter substrate-binding protein

PA0691

PA0691

8.94

203.30

0.45

Hypothetical protein

PA4382

PA4382

8.72

442.90

1.13

Hypothetical protein

PA3382

phnE

8.71

267.00

0.69

Phosphonate transporter PhnE

PA4350

PA4350

8.65

1004.08

2.68

Hypothetical protein

PA3380

PA3380

8.29

243.00

0.83

Hypothetical protein

PA4623

PA4623

8.17

2857.47

10.66

Hypothetical protein

PA3378

PA3378

8.11

284.24

1.09

Hypothetical protein

PA3381

PA3381

8.09

203.83

0.80

Transcriptional regulator

PA3376

PA3376

8.01

188.62

0.79

Phosphonate C-P lyase system protein PhnK

PA3280

oprO

8.01

1907.03

7.95

Pyrophosphate-specific outer membrane porin OprO

PA3377

PA3377

8.00

374.09

1.57

Hypothetical protein

PA3384

phnC

7.99

406.79

1.71

Phosphonate ABC transporter ATP-binding protein

PA0692

PA0692

7.97

218.80

0.93

Hypothetical protein

PA4354

PA4354

7.96

8259.51

36.35

Hypothetical protein

PA0694

exbD2

7.96

260.44

1.14

Transporter ExbD

PA2803

PA2803

7.95

159.82

0.70

Hypothetical protein

PA1555.1

ccoQ2

− 4.94

72.06

2569.51

Cytochrome C oxidase cbb3-type subunit CcoQ

PA5171

arcA

− 4.96

127.12

4229.36

Arginine deiminase

PA5373

betB

− 4.99

27.43

927.48

Betaine aldehyde dehydrogenase

PA5172

arcB

− 5.00

94.84

3244.08

Ornithine carbamoyltransferase

PA0516

nirF

− 5.01

31.55

1090.83

Heme d1 biosynthesis protein NirF

PA4221

fptA

− 5.10

4.54

165.71

Fe(III)-pyochelin outer membrane receptor

PA0518

nirM

− 5.11

39.30

1493.16

Cytochrome C-551

PA0049

PA0049

− 5.19

3.95

153.21

Hypothetical protein

PA5173

arcC

− 5.31

73.26

3107.41

Carbamate kinase

PA0519

nirS

− 5.41

60.36

2744.40

Nitrite reductase

PA2109

PA2109

− 5.86

1.75

107.96

Hypothetical protein

PA5372

betA

− 5.99

3.10

209.46

Choline dehydrogenase

PA4225

pchF

-6.37

1.61

141.55

Pyochelin synthetase

PA4230

pchB

− 6.48

1.44

144.11

Isochorismate-pyruvate lyase

PA4888

desB

− 6.94

1.23

160.81

Acyl-CoA desaturase

PA2114

PA2114

− 7.02

4.57

631.58

Major facilitator superfamily transporter

PA2111

PA2111

− 7.26

5.09

835.52

Hypothetical protein

PA4889

PA4889

− 7.30

1.52

256.77

Oxidoreductase

PA2113

opdO

− 7.94

1.88

492.54

Pyroglutatmate porin OpdO

PA2112

PA2112

− 7.96

2.10

561.56

Hypothetical protein