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Table 1 Overview of process parameters of bioreactor batch cultivations, including yield coefficients, highest surfactin titer Pmax [mg/L], highest biomass Xmax [g/L], highest ComX activity ComXmax [MU], as well as the ComX activity at the end of the cultivation ComX tend [MU]

From: Modeling the time course of ComX: towards molecular process control for Bacillus wild-type cultivations

Cultivation

Bioreactor cultivation

Parameter

20 g/L

40 g/L

60 g/L

Xmax [g/L]

5.7 ± 0.6

20 h

5.4 ± 0.4

32 h

5.0 ± 0.1

24 h

Pmax [mg/L]

800.5 ± 81.3

48 h

1346.6 ± 100.3

40 h

885.7 ± 224.2

44 h

ComXmax [MU]

205.6 ± 4.0

20 h

215.9 ± 17.6

16 h

168.3 ± 11.6

12 h

ComX [MU] tend

163.7 ± 20.5

48 h

134.2 ± 19.9

44 h

131.3 ± 6.6

48 h

YX/S [g/g] at X≥90%

0.29

0.15

0.21

YP/S [g/g] at P≥90%

0.04

0.04

0.03

YP/X [g/g] at P≥90%/X≥90%

0.26

0.49

0.33

µmax [1/h]

0.71

0.52

0.66

qoverall [g/(g·h)]

0.01

0.02

0.01