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Table 1 Overview of process parameters of bioreactor batch cultivations, including yield coefficients, highest surfactin titer Pmax [mg/L], highest biomass Xmax [g/L], highest ComX activity ComXmax [MU], as well as the ComX activity at the end of the cultivation ComX tend [MU]

From: Modeling the time course of ComX: towards molecular process control for Bacillus wild-type cultivations

Cultivation Bioreactor cultivation
Parameter 20 g/L 40 g/L 60 g/L
Xmax [g/L] 5.7 ± 0.6 20 h 5.4 ± 0.4 32 h 5.0 ± 0.1 24 h
Pmax [mg/L] 800.5 ± 81.3 48 h 1346.6 ± 100.3 40 h 885.7 ± 224.2 44 h
ComXmax [MU] 205.6 ± 4.0 20 h 215.9 ± 17.6 16 h 168.3 ± 11.6 12 h
ComX [MU] tend 163.7 ± 20.5 48 h 134.2 ± 19.9 44 h 131.3 ± 6.6 48 h
YX/S [g/g] at X≥90% 0.29 0.15 0.21
YP/S [g/g] at P≥90% 0.04 0.04 0.03
YP/X [g/g] at P≥90%/X≥90% 0.26 0.49 0.33
µmax [1/h] 0.71 0.52 0.66
qoverall [g/(g·h)] 0.01 0.02 0.01