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AMB Express
Fig. 1 | AMB Express

Fig. 1

From: Sulforaphane inhibits self-renewal of lung cancer stem cells through the modulation of sonic Hedgehog signaling pathway and polyhomeotic homolog 3

Fig. 1

Inhibitory effect of SFN on cell proliferation. a Inhibitory effect of SFN on viability of A549 and H460 cells in a dose-dependent manner following treatments with 0, 2, 4, 6, 8, 10 and 12 μmol/L SFN for 48 h by MTT assay. b Inhibitory effect of SFN on cell density of A549 and H460 cells following treatments with 8 μmol/L SFN for 48 h by optical microscope. c, d CD133+ cells were isolated from human lung cancer A549 and H460 cells by Macs. Before sorting, the positive rate of CD133 are 2.8% and 2.4%. And after sorting, the positive rate of CD133 are 96.4% and 97.8% in A549 cells and H460 cells, respectively. e, f The tumor sphere volume of A549/CD133+ and H460/CD133+ cells were inhibited by SFN in a dose-dependent manner

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