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Table 4 Log viable count of P. aeruginosa in different organs of animals in different animal groups (P value < 0.001)

From: In vivo evaluation of a recombinant N-acylhomoserine lactonase formulated in a hydrogel using a murine model infected with MDR Pseudomonas aeruginosa clinical isolate, CCASUP2

Group Description Mean bacterial count ± SD
Blood Log no. of CFU/ml Lung Log no. of CFU/g Liver Log no. of CFU/g
Group N Normal (control) 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0
Group B Burned uninfected (control) 1.84 ± 0.39 1.69 (0.5) 1.602 ± 0.28
Group C Burned, infected, untreated (control) 4.68 ± NAa 4.7 ± NAa 5.05 ± NAa
Group 1 Burned, infected treated with Ahl-1 lactonase hydrogel (test) 0.536 ± 0.09 1 ± 0.29 2.3 ± 0.41
Group 2 Burned, infected, treated with vehicle (control for vehicle) 3.78 ± 1.2 5.114 ± 0.3 4.6 ± 0.56
  1. *NA Not available