Zinc oxide nanoparticles conjugated with clinically-approved medicines as potential antibacterial molecules

AMB Express

Table 4 MIC₅₀ (μg/mL) of ZnO-NPs and drugs-loaded ZnO-NPs suspension against Gram-negative and Gram-positive bacteria

Bacteria	CEFT	ZnO-CEFT	QTG	ZnO-QTG	NAR	ZnO-NAR	AMB	ZnO-AMB	AMPI	ZnO-AMPI	ZnONPs
Bacteria	MIC₅₀	MIC₅₀	MIC₅₀	MIC₅₀	MIC₅₀	MIC₅₀	MIC₅₀	MIC₅₀	MIC₅₀	MIC₅₀	MIC₅₀
E. coli K1	23	14	> 500	> 500	> 500	> 500	> 500	> 500	123	64	290
P. aeruginosa	130	128	> 500	340	> 500	> 500	> 500	390	110	95	255
S. marcescens	55	19	310	245	350	275	470	325	56	21	245
MRSA	16	4	400	114	> 500	270	> 500	236	170	118	158
S. pyogenes	14	6	340	125	420	189	485	210	26	18	130
S. pneumoniae	11	4	90	55	88	52	> 500	270	22	9	95