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Table 1 Phospho/Unphospho Ratio change in F4ac∆faeG vs F4ac infected cells

From: Deletion of FaeG alleviated Enterotoxigenic Escherichia coli F4ac-induced apoptosis in the intestine

Phosphorylation site Gene symbol F4ac∆faeG Phospho/Unphospho ratio (mean ± SD) F4ac Phospho/Unphospho ratio (mean ± SD) Fold change (F4ac∆faeG/F4ac) Apoptosis process or type
Abl1 (Phospho-Tyr204) ABL1 0.217 ± 0.017 0.114 ± 0.016 1.90 Intrinsic (or mitochondrial)
ASK1 (Phospho-Ser83) MAP3K5 1.347 ± 0.248 0.852 ± 0.233 1.58 Intrinsic (or mitochondrial)
XIAP (Phospho-Ser87) XIAP 0.563 ± 0.013 0.919 ± 0.050 0.61 Intrinsic
FKHR (Phospho-Ser256) FOXO1 1.039 ± 0.075 2.172 ± 1.433 0.48 Intrinsic or extrinsic
Cyclin D1 (Phospho-Thr286) CCND1 0.213 ± 0.101 0.411 ± 0.263 0.52 Intrinsic
p44/42 MAPK (Phospho-Tyr204) MAPK3 1.102 ± 0.003 1.775 ± 0.722 0.62 Not specific
BID (Phospho-Ser78) BID 0.418 ± 0.233 0.673 ± 0.093 0.62 Intrinsic or extrinsic
Caspase 3 (Phospho-Ser150) CASP3 0.888 ± 0.019 1.352 ± 0.037 0.66 Intrinsic or extrinsic
Caspase 9 (Phospho-Tyr153) CASP9 0.194 ± 0.079 0.333 ± 0.088 0.58 Intrinsic or extrinsic
CDK2 (Phospho-Thr160) CDK2 1.087 ± 0.017 2.234 ± 0.078 0.49 DNA damage (related to FOXO1)
Cortactin (Phospho-Tyr421) CTTN 1.217 ± 0.009 5.418 ± 0.196 0.22 Extrinsic
GSK3 alpha (Phospho-Ser21) GSK3A 1.147 ± 0.060 1.955 ± 0.797 0.59 Intrinsic or extrinsic
NFkB-p100/p52 (Phospho-Ser869) RELA 1.761 ± 0.696 0.955 ± 0.033 1.84 Not specific
Raf1 (Phospho-Ser259) RAF1 4.060 ± 0.444 2.561 ± 2.560 1.59 Intrinsic (related to ASK1)
STAT3 (Phospho-Tyr705) STAT3 0.858 ± 0.017 1.307 ± 0.566 0.66 Intrinsic or extrinsic
NFkB-p65 (Phospho-Thr435) RELA 2.020 ± 1.050 3.192 ± 0.443 0.63 Not specific
SP1 (Phospho-Thr739) SP1 1.082 ± 0.052 3.159 ± 2.783 0.34 Not specific
LYN (Phospho-Tyr507) LYN 0.134 ± 0.064 0.242 ± 0.035 0.55 Not specific
HSP27 (Phospho-Ser82) HSPB1 1.344 ± 0.084 2.209 ± 0.424 0.61 Intrinsic
Ezrin (Phospho-Thr566) EZR 0.514 ± 0.269 0.293 ± 0.004 1.75 Not specific (related to XIAP)
GRB10 (Phospho-Tyr67) GRB10 1.093 ± 0.006 0.712 ± 0.239 1.53 Not specific (related to Bim)
Synuclein alpha (Phospho-Tyr125) SNCA 0.993 ± 0.030 2.209 ± 1.905 0.45 Intrinsic
VEGFR2 (Phospho-Tyr1175) KDR 1.034 ± 0.097 1.924 ± 1.630 0.54 Intrinsic
PKC zeta (Phospho-Thr410) PRKCZ 0.947 ± 0.016 2.130 ± 1.783 0.44 Extrinsic (related to Fas)
Estrogen Receptor-alpha (Phospho-Ser104) ESR1 2.412 ± 0.150 0.728 ± 0.285 3.31 Extrinsic
Estrogen Receptor-alpha (Phospho-Ser167) ESR1 1.159 ± 0.015 2.406 ± 1.570 0.48 Extrinsic
CaMK2A (Phospho-Thr286) CAMK2A 0.318 ± 0.015 0.206 ± 0.013 1.54 Ca2+-dependent apoptosis
eEF2K (Phospho-Ser366) EEF2K 1.011 ± 0.005 0.654 ± 0.183 1.54 Intrinsic or extrinsic
Ras-GRF1 (Phospho-Ser916) RASGRF1 0.609 ± 0.071 0.396 ± 0.007 1.54 Not specific