Fig. 1

Schematic representation of increasing glycolysis by deletions of kcs1 and arg82 improved SAM production in Saccharomyces cerevisiae. a The glycolytic intermediates are linked to SAM metabolism; b Pathway for the synthesis of inositol polyphosphates. The color of blue represents the glycolysis pathway enhanced by deletions of kcs1 and arg82; The color of red represents the IPs metabolism. The black triangle represents the introduction of heterologous gene; The black rectangle represents gene over-expression; The red cross represents gene deletion