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Table 4 Keratinase–based formulation in commercial use (some information were adapted from Hassan et al. 2020 and Srivastava et al. 2020)

From: Microbial keratinase and the bio-economy: a three-decade meta-analysis of research exploit

Enzyme

Microbial producer

Formulation

Usesa

Manufacturer/supplier

Keratinase

B. licheniformis

Keratoclean® sensitive PB

Skin care products

PROTEOS Biotech

Keratinase

B. licheniformis

Versazyme®

Animal feed preparation, keratin and collagen degradation

BioResource International, Inc

Keratinase

B. licheniformis

Valkerase®

Feather meal processing

BioResource International, Inc

Keratinolytic protease

B. licheniformis

CIBENZA® DP100

Poultry and swine feed ingredient digestion

Novus International, Inc

Keratinase

B. licheniformis

Keratoclean® HYDRA PB

Skin care products

PROTEOS Biotech

Keratinase

B. licheniformis

Keratoclean® BP

Skin care products

PROTEOS Biotech

Keratinase

B. licheniformis

Prionzyme M

Biodecontamination

Genencor International, Inc

Keratinase

B. licheniformis

FEED-0001

Insoluble keratin degradation

Creative Enzymes®

Keratinase

Recombinant Escherichia coli BL21

NATE-0853

Enzymatic treatment of EB, GAGs and cells

Creative Enzymes®

Keratinase

B. licheniformis

PURE100 KERATINASE

Biomedical, pharmaceutical and cosmetic applications

PROTEOS Biotech

  1. aEB elementary body, GAGs glycosaminoglycans