Skip to main content

Table 1 Comparison of octanol/water partition coefficient values determined by the shake-flask method and calculated by the theoretical method

From: Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives

Compound log P1 average value log P2
Eugenol 2.20 ± 0.001c 2.49
EChA 2.43 ± 0.001ab 3.11
EDChA 2.65 ± 0.001ab 3.73
ETChA 2.75 ± 0.002a 4.35
DChAA 0.95 ± 0.002e 0.80
TChAA 1.51 ± 0.002d 1.42
  1. 1 determined by the shake-flask method; mean ± S.D. (n = 3)
  2. 2 log P calculated in the MestReNova program, different letters–values are significantly different, mass substance in the acceptor fluid (P < 0.001)