From: Rhein laden pH-responsive polymeric nanoparticles for treatment of osteoarthritis
Formulation | Size (nm) | Poly dispersity index (PDI) | Zeta-potential (mV) | % Entrapment Efficiency (± SD) |
---|---|---|---|---|
PLGA-NPs | 116.8 ± 1.5 | 0.12 ± 0.04 | − 6.8 ± 1.27 | – |
Rh-PLGA-NPs | 134.6 ± 2.4 | 0.15 ± 0.013 | − 16 ± 1.13 | 64.4 ± 2.11 |
Rh-PLGA-NPs@NH4 | 190.7 ± 1.2 | 0.14 ± 0.015 | − 22 ± 1.12 | 46.7 ± 0.10 |