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Table 2 Effects of nisin, licorice polyphenols (glabridin, licoricidin, licochalcone A), and chlorhexidine at a sub-inhibitory concentration (1/4 MIC) on biofilm formation by E. faecalis ATCC 19433

From: Biocompatible combinations of nisin and licorice polyphenols exert synergistic bactericidal effects against Enterococcus faecalis and inhibit NF-κB activation in monocytes

Compound (µg/mL) Relative growth (%) Biofilm formation (%)
None 102.3 ± 2.5 101.5 ± 4.9
Nisin (3.125 µg/mL) 109.1 ± 9.9 76.5 ± 6.6*
Glabridin (6.25 µg/mL) 101.4 ± 2.9 103.8 ± 6.8
Licoricidin (1.56 µg/mL) 104.4 ± 2.2 68.4 ± 4.9*
Licochalcone A (3.125 µg/mL) 97.1 ± 0.9 91.4 ± 8.7
Chlorhexidine (1.56 µg/mL) 106.8 ± 3.7 62.5 ± 1.5*
  1. *Significant reduction (p < 0.01) compared to control cultures without compounds