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Table 4 Minimum inhibitory concentration (MIC) of Berberis aristata extracts, its partially purified phytoconstituents (PPPs) and standard antibiotics

From: Scientific validation of the antimicrobial and antiproliferative potential of Berberis aristata DC root bark, its phytoconstituents and their biosafety

Microorganisms

MIC (mg/mL)

Aqa

EAb

Alkaloids

Flavonoids

Diterpenes

Gentamicin

Chloramphenicol

SA

2.5

0.05

1

0.1

0.5

0.0002

0.01

SE

25

0.1

3

3

3

0.01

0.01

MRSA

5

0.05

5

0.1

0.05

0.005

0.01

EC

5

0.05

5

3

3

0.005

0.01

EF

22.5

0.1

ND

1

1

0.03

0.3

KP1

2.5

0.05

1

0.05

0.1

0.0002

0.01

KP2

ND

0.1

1

0.5

0.7

0.0005

0.001

SF

ND

0.05

ND

ND

5

0.005

0.01

ST1

ND

0.05

ND

ND

ND

0.005

0.1

ST2

15

0.05

1

0.05

0.1

0.0003

0.001

PA

5

0.05

10

10

0.05

0.005

0.7

CA

7.5

0.05

0.7

0.1

0.05

0.0003c

ND

CT

ND

0.5

ND

1

1

0.1c

ND

  1. SA, Staphylococcus aureus; SE, Staphylococcus epidermidis; EC, Escherichia coli; KP1, Klebsiella pneumoniae 1; KP2, Klebsiella pneumoniae 2; SF, Shigella flexneri; ST1, Salmonella typhimurium 1; ST2, Salmonella typhimurium 2; PA, Pseudomonas aeruginosa; CA, Candida albicans; CT, Candida tropicalis; MRSA, methicillin-resistant Staphylococcus aureus; ND, not determined
  2. aAqueous extract
  3. bEthyl acetate extract
  4. cAmphotericin B