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Table 1 Minimum inhibitory concentrations (MICs) of the EntP peptide and various antibiotics

From: Expression in eukaryotic cells and purification of synthetic gene encoding enterocin P: a bacteriocin with broad antimicrobial spectrum

Strain Antimicrobial activity MIC (ug/ml)
EntP Ampicillin Ceftazidime Vancomycin Piperacillin Gentamicin
Gram positive bacteria
 Staphylococcus aureus ATCC 25923 8 ≤ 1 ≤ 2 ≤ 1 ND ≤ 1
 Staphylococcus aureus ATCC 29213 8 ≤ 1 ≤ 2 ≤ 1 ND ≤ 1
 Enterococcus faecalis ATCC 29212 16 ≤ 1 ≤ 4 ≤ 1 ND ≤ 1
 Listeria monocytogenes 32 2 ≤ 4 1 4 8
Gram negative bacteria
 E. coli ATCC 25922 128 ≤ 2 ≤ 2 ND ≤ 8 ≤ 1
 Salmonella typhi 16 2 4 ND 4 ≤ 2
 Salmonella paratyphi C ND 2 4 ND ≤ 8 ≤ 1
 Shigella dysenteriae 128 4 ≤ 2 ND 4 4
 Pseudomonas aeruginosa ATCC 27853 8 ND 2 ND ≤ 8 ≤ 16
Resistant strains
 MRSA ATCC 33591 64 ND 16 ≥ 16 ND ≥ 16
 VRE 64 ND 32 ≥ 32 ND ≥ 16
 Pseudomonas aeruginosa VIM+ 256 ND ≥ 32 ND ≥ 128 ≥ 16
 Acinetobacter baumannii ATCC 13304 128 ND ≥ 32 ND ≥ 64 ≥ 16
 Klebsiella pneumonia ATCC 700603 8 > 128 ≥ 16 ND ≥ 128 ≥ 16
  1. Data are collected as MICs according to the Clinical and Laboratory Standards Institute (CLSI)
  2. ND not determined
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