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Fig. 4 | AMB Express

Fig. 4

From: Berberine attenuate staphylococcal enterotoxin B-mediated acute liver injury via regulating HDAC expression

Fig. 4

BBR was effective at downregulating class I HDAC after activation of SEB. Splenocytes were treated with SEB, in the absence or presence of 1 or 2 μM BBR or 100 nM TSA for 24 h. a The HDAC activity was investigated by colorimetric analysis. b, c The mRNA expression of class I and II HDAC enzymes was detected in the treated splenocytes by qRT-PCR analysis. d The protein levels of H3K9Ac were examined by western blot in the treated splenocytes. *P < 0.05. SEB group versus Vehicle or SEB + BBR or SEB + TSA group, respectively

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