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Table 7 Effect of resin addition on growth of P. acidilactici in fed-batch fermentation using 2 L stirred tank bioreactor

From: Strategies for improving production performance of probiotic Pediococcus acidilactici viable cell by overcoming lactic acid inhibition

Kinetic parameter Fed-batch without resin Fed-batch with resin
Maximum viable cell concentration (cfu/mL) 1.1 × 1013 ± 0.14b 1.0 × 1014 ± 0.07a
Time to reach maximum viable cell concentration (h) 14b 20a
Viable cell yield (cfu/gGlucose) 1.2 × 1015 ± 0.11b 7.2 × 1016 ± 0.12a
Viable cell productivity (cfu/mL h) 7.9 × 1011 ± 0.12b 5.1 × 1012 ± 0.08a
Lactic acid accumulated (g/L) 8.12 ± 0.11b 8.78 ± 0.06a
Lactic acid produced (g/L) 8.12 ± 0.11b 12.24 ± 0.08a
Lactic acid yield (g/gGlucose) 0.89 ± 0.06a 0.72 ± 0.06b
Lactic acid productivity (g/L h) 0.28 ± 0.08b 0.43 ± 0.04a
  1. The results presented are the average of triplicate experiments
  2. Statistically significant coefficient (P < 0.05) are expressed as mean ± SE
  3. a,bMean values with the different letters are significantly different