Fig. 2
From: Production of bioactive liver-targeting interferon Mu-IFN-CSP by soluble prokaryotic expression
Sequences and structure alignment of native IFN-CSP and Mu-IFN-CSP. A Amino acid sequences alignment of native IFN-CSP and Mu-IFN-CSP. The amino acid residues in the blue color regions are identical. The amino acid residues in other color regions are mutation positions. B Structure alignment of native IFN-CSP and Mu-IFN-CSP. Green denotes native IFN-CSP; red denotes Mu-IFN-CSP. Compared with native IFN-CSP, the Mu-IFN-CSP formed three structure changes (a, b and c). C The RMSDs of the molecular dynamic simulation systems. D The total energy of native IFN-CSP and Mu-IFN-CSP during MD simulations