In vitro and in vivo antibacterial effect of NZ2114 against Streptococcus suis type 2 infection in mice peritonitis models

AMB Express

Table 1 MIC and MBC assays of NZ2114 and ampicillin to S. suis, S. aureus, S. pneumonia, and E. coil

Strains	Source	MIC (μM)		MBC (μM)
Strains	Source	NZ2114	Ampicillin	NZ2114	Ampicillin
S. suis CVCC606	CVCC^a	0.03	0.17	0.03	0.34
S. suis CVCC3309	CVCC	0.03	0.34	0.06	0.34
S. suis CVCC3928	CVCC	0.06	0.34	0.06	1.02
S. aureus ATCC25923	CVCC	0.03	1.35	0.06	1.35
S. aureus ATCC6538	CGMCC^b	0.11	1.35	0.11	2.69
S. aureus ATCC43300	CGMCC	0.9	10.78	0.9	21.56
Streptococcus pneumoniae CGMCC1.8722	CGMCC	0.45	1.35	0.9	2.69
S. pneumoniae CVCC2350	CVCC	0.9	2.69	1.8	5.38
S. pneumoniae CVCC31968	CVCC	0.9	2.69	0.9	2.69
E.coli CVCC195	CVCC	≥29.09	0.31	≥29.09	0.31
E.coli CVCC1515	CVCC	≥29.09	NT	≥29.09	NT