Fig. 1
From: Functional expression and evaluation of heterologous phosphoketolases in Saccharomyces cerevisiae
Native and heterologous metabolic pathways for improved cytosolic acetyl-CoA production in S. cerevisiae. The native enzymatic pathways are indicated with light blue arrows, while the colored arrows indicate the alternative pathways that have been evaluated for cytosolic acetyl-CoA production in yeast. A-Ald acetylating acetaldehyde dehydrogenase, Ac-CoA acetyl-CoA, AcAld acetaldehyde, Ace acetate, Acl ATP citrate lyase, AcP acetyl-phosphate, Cit citrate, E4P erythrose-4-phosphate, F6P fructose-6-phosphate, G3P glycerol-3-phosphate, G6P glucose-6-phosphate, Pdh cyto cytosolic pyruvate dehydrogenase complex, Pfl pyruvate formate lyase, Pta phosphotransacetylase, Pyr pyruvate, R5P ribose-5-phosphate, Ri5P ribulose-5-phosphate, S7P seduheptulose-7-phosphate, X5P xylulose-5-phosphate, Xfpk phosphoketolase