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Table 1 Factor values and responses in the various runs

From: Disruption of Pseudomonas putida by high pressure homogenization: a comparison of the predictive capacity of three process models for the efficient release of arginine deiminase

Run A (g/L) B (bar) C ADI activity (U/mL) Total protein release (g/L) Cell disruption (%)
Actual RSM predicted ANN predicted SVM predicted Actual RSM predicted ANN predicted SVM predicted Actual RSM predicted ANN predicted SVM predicted
1 200 413.7 2 22.5 23.2 23.0 22.6 2.7 2.6 3.0 2.8 63.3 63.9 64.6 63.4
2 100 965.3 1 20.1 20.1 17.8 20.2 2.8 2.8 2.9 2.9 75.5 73.6 76.3 75.4
3 300 413.7 3 22.6 22.5 23.6 22.5 4.9 4.8 4.3 4.8 70.2 71.9 77.7 70.3
4 300 965.3 1 23.2 23.1 23.7 23.3 4.7 4.6 4.5 4.6 65.5 66.4 67.3 65.4
5 100 965.3 3 22.5 22.8 21.5 22.6 2.4 2.3 2.8 2.4 93.0 94.5 89.3 92.9
6 100 689.5 2 19.5 19.4 17.2 19.6 2.2 2.2 2.8 2.1 86.4 87.3 80.7 86.5
7 300 689.5 2 24.4 24.3 23.6 24.8 4.0 4.2 4.4 4.2 78.9 79.0 73.2 78.9
8 200 689.5 1 25.5 26.3 24.9 25.6 3.1 3.0 2.9 2.9 57.8 60.0 58.3 57.9
9 200 689.5 2 25.2 25.0 25.2 25.1 3.5 3.0 3.1 3.0 80.7 79.7 79.5 79.7
10 300 689.5 3 22.1 22.6 22.6 22.2 5.5 5.4 4.7 5.4 85.4 84.5 83.9 85.3
11 200 689.5 2 25.4 25.0 25.2 25.1 3.1 3.0 3.1 3.0 84.3 79.7 79.5 79.7
12 200 689.5 2 25.0 25.0 25.2 25.1 2.8 3.0 3.1 3.0 79.6 79.7 79.5 79.7
13 300 413.7 1 27.7 27.4 26.1 27.6 3.1 3.2 3.8 3.2 43.1 41.3 42.4 43.0
14 200 689.5 3 26.1 25.2 25.0 24.7 3.3 3.6 3.4 3.5 86.7 85.7 86.7 86.8
15 200 965.3 2 25.3 24.5 24.8 25.2 3.1 3.3 3.6 3.4 82.5 83.1 84.9 82.6
16 200 689.5 2 23.7 25.0 25.2 25.1 2.8 3.0 3.1 3.0 76.7 79.7 79.5 79.7
17 100 413.7 1 18.0 17.5 19.0 17.9 2.0 2.1 2.3 2.1 47.1 47.8 48.3 47.2
18 200 689.5 2 25.0 25.0 25.2 25.1 3.0 3.0 3.1 3.0 80.0 79.7 79.5 79.7
19 200 689.5 2 25.1 25.0 25.2 25.1 3.1 3.0 3.1 3.0 79.0 79.7 79.5 79.7
20 100 413.7 3 15.7 15.8 17.0 15.8 2.4 2.4 2.7 2.4 82.3 81.2 84.0 82.2
  1. A, Cell mass concentration; B, Operating pressure; C, number of passes