Table 5 Seventeen trial Box–Behnken design matrix for the experimental variables with coded values
From: Improved production of melanin from Aspergillus fumigatus AFGRD105 by optimization of media factors
Runs | Experimental parameter | Response (mg/L) | ||
|---|---|---|---|---|
A | B | C | ||
1 | −1 | 0 | −1 | 16.5 |
2 | +1 | 0 | −1 | 17.1 |
3 | −1 | +1 | 0 | 13.5 |
4 | 0 | −1 | +1 | 23.5 |
5 | 0 | 0 | 0 | 19.5 |
6 | 0 | 0 | 0 | 14.3 |
7 | +1 | +1 | 0 | 13.2 |
8 | +1 | −1 | 0 | 20.1 |
9 | −1 | −1 | 0 | 19.5 |
10 | 0 | 0 | 0 | 11.7 |
11 | 0 | 0 | 0 | 12.3 |
12 | −1 | 0 | +1 | 22.5 |
13 | 0 | −1 | −1 | 29.3 |
14 | +1 | 0 | +1 | 31.9 |
15 | 0 | +1 | −1 | 22.4 |
16 | 0 | 0 | 0 | 21.6 |
17 | 0 | +1 | +1 | 32.6 |