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Table 5 Seventeen trial Box–Behnken design matrix for the experimental variables with coded values

From: Improved production of melanin from Aspergillus fumigatus AFGRD105 by optimization of media factors

Runs Experimental parameter Response (mg/L)
A B C
1 −1 0 −1 16.5
2 +1 0 −1 17.1
3 −1 +1 0 13.5
4 0 −1 +1 23.5
5 0 0 0 19.5
6 0 0 0 14.3
7 +1 +1 0 13.2
8 +1 −1 0 20.1
9 −1 −1 0 19.5
10 0 0 0 11.7
11 0 0 0 12.3
12 −1 0 +1 22.5
13 0 −1 −1 29.3
14 +1 0 +1 31.9
15 0 +1 −1 22.4
16 0 0 0 21.6
17 0 +1 +1 32.6