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Table 1 Pathway analysis among up- and down- regulated proteins of C. albicans

From: Description of the interaction between Candida albicans and macrophages by mixed and quantitative proteome analysis without isolation

Up-regulated C. albicans proteins

Down-regulated C. albicans proteins

Fold enrichment

KEGG pathway term

Fold enrichment

KEGG pathway term

11

Fatty acid metabolism

13

Ribosome

11

Glyoxylate and dicarboxylate metabolism

7.7

Synthesis and degradation of ketone bodies

7.5

Galactose metabolism

5.7

Propanoate metabolism

7.5

Glycerolipid metabolism

5.7

Butanoate metabolism

7.5

Methane metabolism

5.7

beta-Alanine metabolism

7.5

alpha-Linolenic acid metabolism

4.6

Valine, leucine and isoleucine degradation

7.0

Pyruvate metabolism

4.2

Fructose and mannose metabolism

6.4

Citrate cycle (TCA cycle)

3.8

Vitamin B6 metabolism

6.4

Nitrogen metabolism

3.3

Citrate cycle (TCA cycle)

5.6

Butanoate metabolism

3.3

Phosphatidylinositol signaling system

4.5

Pantothenate and CoA biosynthesis

3.0

Glycolysis/Gluconeogenesis

4.1

Fructose and mannose metabolism

2.9

Pyruvate metabolism

3.9

Glycolysis/Gluconeogenesis

2.9

Terpenoid backbone biosynthesis

3.9

Arginine and proline metabolism

2.6

Galactose metabolism

3.9

Alanine, aspartate and glutamate metabolism

2.6

Lysine biosynthesis

3.6

Proteasome

2.3

Amino sugar and nucleotide sugar metabolism

3.4

Amino sugar and nucleotide sugar metabolism

2.3

Lysine degradation

2.8

Propanoate metabolism

2.2

Aminoacyl-tRNA biosynthesis

2.8

Biosynthesis of unsaturated fatty acids

2.1

Glutathione metabolism

2.5

Lysine biosynthesis

1.8

Valine, leucine and isoleucine biosynthesis

2.5

Tryptophan metabolism

1.6

Starch and sucrose metabolism

2.2

Sulfur metabolism

1.5

Purine metabolism

2.0

Glutathione metabolism

1.5

Glycine, serine and threonine metabolism

2.0

Phenylalanine metabolism

  

2.0

Oxidative phosphorylation

  

2.0

Cysteine and methionine metabolism

  

1.9

Phenylalanine, tyrosine and tryptophan biosynthesis

  

1.9

Tyrosine metabolism

  

1.9

Selenoamino acid metabolism

  

1.7

Glycerophospholipid metabolism

  

1.7

Valine, leucine and isoleucine metabolism

  

1.6

Starch and sucrose metabolism