Figure 1

a Wound healing capacity of TR146 epithelial cells confronted with inserts containing 5.5–6 log CFU of monocultures of different oral species. The relative area of the wound after 24 h is plotted (mean + SD; *p < 0.05). The black bars represent data from experiments performed without pre-incubation of the microbial cells on the insert, the white bars represent data from experiments with a 4 h pre-incubation step of the microbiota before confrontation with the epithelial cells. Mean microbial counts of the different species present on the filters after 24 h of co-culture with TR146 epithelial cells are depicted (N.D. = not detected). b Cytokine analysis of the basal conditioned medium. The microbial monocultures of different oral species were pre-incubated for 4 h before confrontation with the TR146 cells for 24 h. Relative concentrations are shown (mean + SD; *p < 0.05).