Figure 2
Central carbon metabolism of PHB producing S. cerevisiae grown on different substrates. a) Glucose, b) Ethanol and c) Mixed-substrate of glucose and ethanol. ADH2 = alcohol dehydrogenase; ALD6 = aldehyde dehydrogenase; ACS = acetyl-CoA synthetase (acsL641P); ERG10 = acetyl-CoA C-acetyltransferase; PhaA (β-ketothiolase); PhaB (acetoacetyl-CoA reductase); PhaC (polyhydroxyalkanoate synthase). ICI = isocitrate; CIT = citrate: OXA = oxaloacetate; MAL = malate; Glyox = glyoxylate.