Table 2 SIM combined with polymyxins against MRSA
From: Simeprevir restores the anti-Staphylococcus activity of polymyxins
Strains | Antimicrobials | MIC Alone(µg/mL) | MIC In combination(µg/mL) | FICI | Outcome |
|---|---|---|---|---|---|
ATCC 43,300 | PB(S) | 64 | 8 | 0.375 | Synergy |
SIM | 4 | 1 | |||
PB | 64 | 16 | 0.5 | Synergy | |
SIM | 4 | 1 | |||
PE | 16 | 4 | 0.5 | Synergy | |
SIM | 4 | 1 | |||
USA300 | PB(S) | 32 | 8 | 0.5 | Synergy |
SIM | 4 | 1 | |||
PB | 16 | 4 | 0.5 | Synergy | |
SIM | 4 | 1 | |||
PE | 64 | 8 | 0.375 | Synergy | |
SIM | 4 | 1 |