Fig. 6
From: Simeprevir restores the anti-Staphylococcus activity of polymyxins
In vivo antimicrobial effect of SIM alone or in combination with PB(S)/PE. (A) Viable cell counts in abscess after treatment with PB(S)/PE (30 mg/kg) and SIM (20 mg/kg) alone or in combination. (B) Representative images of the abscesses. (C) Subcutaneous abscess histopathological analysis using H&E staining and immunohistochemistry of TNF-α or IL-6, respectively. Scale: 200 μm. n = 7 mice per group. ns: no statistical significance. *: P < 0.05