Fig. 1
From: Enhancing a Sphaerobacter thermophilus ω-transaminase for kinetic resolution of β- and γ-amino acids
Reaction mechanisms for amino transferases converting β-amino acids. a Kinetic resolution, starting from a racemic β-amino acid to de-aminate one enantiomer and to transfer the amino group to an amino acceptor, in this case pyruvate. b The asymmetric synthesis starts with a prochiral β-keto acid, which is aminated and leads to an enantiopure amino acid. The asymmetric synthesis leads to the other enantiomer, concluding the kinetic resolution