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Table 2 Clinical manifestations of PHN

From: Alterations of the gut microbiota in patients with postherpetic neuralgia

 

PHN (n = 27)

Disease course (month), n (%)

 1–3

13 (48.15%)

 4–6

4 (14.81%)

 7–12

6 (22.22%)

 > 12

4 (14.81%)

Location of lesion, n (%)

 Face (Trigeminal nerve region)

1 (3.70%)

 Neck and upper limbs (Cervical nerve region)

8 (29.63%)

 Trunk (Thoracic nerve region)

16 (59.26%)

 Buttocks and lower limbs (Lumbar and Sacral nerves region)

2 (7.41%)

Preherpetic pain, n (%)

17 (62.96%)

Spontaneous pain, n (%)

25 (92.59%)

Dynamic mechanical allodynia, n (%)

16 (59.26%)

Sensory disturbance, n (%)

 Itching

15 (55.56%)

 Numbness

13 (48.15%)

PHQ-9 (score), n (%)

 No depression (0–4)

10 (37.04%)

 mild (5–9)

7 (25.93%)

 moderate (10–14)

4 (14.81%)

 moderate-severe (15–19)

4 (14.81%)

 Severe (20–27)

2 (7.41%)

GAD-7 (score), n (%)

 No anxiety (0–4)

13 (48.15%)

 Mild (5–9)

12 (44.44%)

 Moderate (10–13)

0 (0%)

 Moderate-severe (14–18)

0 (0%)

 Severe (19–21)

2 (7.41%)

ISI (score), n (%)

 Insomnia without clinical significance (0–7)

6 (22.22%)

 Subclinical insomnia (8–14)

16 (59.26%)

 Clinical insomnia (moderate) (15–21)

4 (14.81%)

 Clinical insomnia (severe) (22–28)

1 (3.70%)

Cold pain, n (%)

 Normal

10 (37.04%)

 Hypalgesia

14 (51.85%)

 Hyperpathia

3 (11.11%)

Heat pain, n (%)

 Normal

15 (55.56%)

 Hypalgesia

8 (29.63%)

 Hyperpathia

4 (14.81%)

Pain intensity (NRS 0–10), n (%)

 No pain (0)

1 (3.70%)

 Mild (1–3)

12 (44.44%)

 Moderate (4–6)

6 (22.22%)

 Severe (7–10)

8 (29.63%)

Itching intensity (NRS 0–10), n (%)

 No itching (0)

9 (33.33%)

 Mild (1–3)

12 (44.44%)

 Moderate (4–6)

5 (18.52%)

 Severe (7–10)

1 (3.70%)

  1. PHQ-9 Patient Health Questionnaire-9, GAD-7 Generalized Anxiety Disorder Screener-7, NRS numerical rating scale, ISI Insomnia Severity Index