Fig. 3

Diacerein inhibits HE01 biofilm formation and spreads mature biofilm. The biofilm inhibitory activity (a) and biofilm dispersive activity (b) of diacerein against HE01 were detected at serial concentrations. The measurement at OD570 nm was taken to measure the biofilm. The data represent the mean ± SD (n = 3), #p < 0.0001 (a). The concentration of diacerein used to eradicate mature biofilms was 1024 μg/ml to 4 μg/ml, from left to right, and for the remaining two wells, DMSO was added to one well, and no drug was added to the other (b)