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Table 4 Differences in regulatory genes transcription between exponential growth (24 h) and stationary phase (41 h) expressed in RPKM

From: Medium-chain-length polyhydroxyalkanoates synthesis by Pseudomonas putida KT2440 relA/spoT mutant: bioprocess characterization and transcriptome analysis

Gene

Locus tag

Description

RPKM 24 h

RPKM 41 h

Fold change

ntrC

PP_5048

Fis family transcriptional regulator

62.1

547.7

8.8

Up

glnK

PP_5234

Regulatory protein

8152.0

47668.9

5.8

Up

lrp

PP_5271

Leucine-responsive regulatory protein

396.2

499.0

1.3

Up

psrA

PP_2144

Transcriptional repressor, TetR family

2028.2

1349.0

1.5

Down

rpoS

PP_1623

Sigma factor RpoS

9969.7

9452.2

1.1

Down

rpoD

PP_0387

Sigma factor RpoD

2845.4

2825.1

1.1

Down

rpoN

PP_0952

Sigma factor RpoN

699.2

558.1

1.3

Down

rpoA

PP_0479

RNA polymerase subunit alpha

5534.4

4088.8

1.4

Down

rpoB

PP_0447

RNA polymerase subunit beta

1443.0

1112.9

1.3

Down

rpoC

PP_0448

RNA polymerase subunit beta

1716.1

1329.8

1.3

Down

crc

PP_5292

Catabolite repression control protein

1860.3

1655.0

1.1

Down

gacS

PP_1650

Sensor kinase

68.7

97.9

1.4

Up

gacA

PP_4099

DNA-binding response regulator GacA

1413.5

1169.3

1.2

Down

Unknown gene

PP_2475

Transcriptional regulator, TetR family

1296.3

17129.2

13.2

Up

Unknown gene

PP_1863

Transcriptional regulator, LysR family

154.7

307.5

1.9

Up