Table 1 Factor values and responses in the various runs
Run | A (g/L) | B (bar) | C | ADI activity (U/mL) | Total protein release (g/L) | Cell disruption (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Actual | RSM predicted | ANN predicted | SVM predicted | Actual | RSM predicted | ANN predicted | SVM predicted | Actual | RSM predicted | ANN predicted | SVM predicted | ||||
1 | 200 | 413.7 | 2 | 22.5 | 23.2 | 23.0 | 22.6 | 2.7 | 2.6 | 3.0 | 2.8 | 63.3 | 63.9 | 64.6 | 63.4 |
2 | 100 | 965.3 | 1 | 20.1 | 20.1 | 17.8 | 20.2 | 2.8 | 2.8 | 2.9 | 2.9 | 75.5 | 73.6 | 76.3 | 75.4 |
3 | 300 | 413.7 | 3 | 22.6 | 22.5 | 23.6 | 22.5 | 4.9 | 4.8 | 4.3 | 4.8 | 70.2 | 71.9 | 77.7 | 70.3 |
4 | 300 | 965.3 | 1 | 23.2 | 23.1 | 23.7 | 23.3 | 4.7 | 4.6 | 4.5 | 4.6 | 65.5 | 66.4 | 67.3 | 65.4 |
5 | 100 | 965.3 | 3 | 22.5 | 22.8 | 21.5 | 22.6 | 2.4 | 2.3 | 2.8 | 2.4 | 93.0 | 94.5 | 89.3 | 92.9 |
6 | 100 | 689.5 | 2 | 19.5 | 19.4 | 17.2 | 19.6 | 2.2 | 2.2 | 2.8 | 2.1 | 86.4 | 87.3 | 80.7 | 86.5 |
7 | 300 | 689.5 | 2 | 24.4 | 24.3 | 23.6 | 24.8 | 4.0 | 4.2 | 4.4 | 4.2 | 78.9 | 79.0 | 73.2 | 78.9 |
8 | 200 | 689.5 | 1 | 25.5 | 26.3 | 24.9 | 25.6 | 3.1 | 3.0 | 2.9 | 2.9 | 57.8 | 60.0 | 58.3 | 57.9 |
9 | 200 | 689.5 | 2 | 25.2 | 25.0 | 25.2 | 25.1 | 3.5 | 3.0 | 3.1 | 3.0 | 80.7 | 79.7 | 79.5 | 79.7 |
10 | 300 | 689.5 | 3 | 22.1 | 22.6 | 22.6 | 22.2 | 5.5 | 5.4 | 4.7 | 5.4 | 85.4 | 84.5 | 83.9 | 85.3 |
11 | 200 | 689.5 | 2 | 25.4 | 25.0 | 25.2 | 25.1 | 3.1 | 3.0 | 3.1 | 3.0 | 84.3 | 79.7 | 79.5 | 79.7 |
12 | 200 | 689.5 | 2 | 25.0 | 25.0 | 25.2 | 25.1 | 2.8 | 3.0 | 3.1 | 3.0 | 79.6 | 79.7 | 79.5 | 79.7 |
13 | 300 | 413.7 | 1 | 27.7 | 27.4 | 26.1 | 27.6 | 3.1 | 3.2 | 3.8 | 3.2 | 43.1 | 41.3 | 42.4 | 43.0 |
14 | 200 | 689.5 | 3 | 26.1 | 25.2 | 25.0 | 24.7 | 3.3 | 3.6 | 3.4 | 3.5 | 86.7 | 85.7 | 86.7 | 86.8 |
15 | 200 | 965.3 | 2 | 25.3 | 24.5 | 24.8 | 25.2 | 3.1 | 3.3 | 3.6 | 3.4 | 82.5 | 83.1 | 84.9 | 82.6 |
16 | 200 | 689.5 | 2 | 23.7 | 25.0 | 25.2 | 25.1 | 2.8 | 3.0 | 3.1 | 3.0 | 76.7 | 79.7 | 79.5 | 79.7 |
17 | 100 | 413.7 | 1 | 18.0 | 17.5 | 19.0 | 17.9 | 2.0 | 2.1 | 2.3 | 2.1 | 47.1 | 47.8 | 48.3 | 47.2 |
18 | 200 | 689.5 | 2 | 25.0 | 25.0 | 25.2 | 25.1 | 3.0 | 3.0 | 3.1 | 3.0 | 80.0 | 79.7 | 79.5 | 79.7 |
19 | 200 | 689.5 | 2 | 25.1 | 25.0 | 25.2 | 25.1 | 3.1 | 3.0 | 3.1 | 3.0 | 79.0 | 79.7 | 79.5 | 79.7 |
20 | 100 | 413.7 | 3 | 15.7 | 15.8 | 17.0 | 15.8 | 2.4 | 2.4 | 2.7 | 2.4 | 82.3 | 81.2 | 84.0 | 82.2 |