Fig. 1From: Metabolic engineering of the mixed-acid fermentation pathway of Escherichia coli for anaerobic production of glutamate and itaconateAnaerobic itaconate pathway in metabolically engineered E. coli. The green bold arrows indicate the introduced pathway consisting of genes encoding citrate synthase (gltA) and aconitase (acnA) from C. glutamicum and cis-aconitate decarboxylase (cadA) from A. terreus. The red lines indicate that phosphate acetyltransferase (pta) and lactate dehydrogenase (ldhA) were deletedBack to article page