Overexpression of miR-32 in Chinese hamster ovary cells increases production of Fc-fusion protein

AMB Express

Table 1 Previous used microRNAs for modifying CHO cells

miR	Product	Effect or Target	References
miR-23a miR-377	Lysosomal sulfatase	Specific Activity	Amadi et al. 2020
miR-106b	IgG	Inhibition of CYLD	Xu et al. 2019
miR-744	mAb	Productivity	Raab et al. 2019
miR-143	mAb/SEPA	Productivity	Schoellhorn et al. 2017
miR-92a	anti-HER2 IgG	Protein secretion	Loh et al. 2017
miR-483	mAb	Productivity	Emmerling et al. 2016
miR-30	SEAP	Ubiquitin pathway	Fischer et al. 2015a, 2015b
miR-23	SEPA	metabolism	Kelly et al. 2015b
miR-34a	SEPA	Cell Growth	Kelly et al. 2015a