Table 4 The AMR genes annotated in this genome and corresponding AMR mechanism
From: Draft genome of Raoultella planticola, a high lead resistance bacterium from industrial wastewater
Genes | ABR mechanism |
|---|---|
katG | Antibiotic activation enzyme |
PLA family | Antibiotic inactivation enzyme |
marA, marB, marR | Antibiotic resistance gene cluster or operon |
alr, ddl, dxr, EF-G, EF-Tu, folA, Dfr, folP, gyrA, gyrB, inhA, fabI, Iso-tRNA, kasA, MurA, rho, rpoB, rpoC, S10p, S12p | Antibiotic target in susceptible species |
bcrC | Antibiotic target protection protein |
acrAB-TolC, acrAD-TolC, acrZ, emrAB-TolC, emrD, macA, macB, mdfA/Cmr, mdtABC-TolC, mdtL, sugE, tolC/OpmH | Efflux pump conferring antibiotic resistance |
gdpD, pgsA | Protein altering cell wall charge conferring antibiotic resistance |
oprB | Protein modulating permeability to antibiotic |
acrAB-TolC, emrAB-TolC, H-NS, oxyR | Regulator modulating expression of antibiotic resistance genes |